The files are R archives and must be loaded with R command 'load'. The file u.sum.fly.rda contains the squared named matrix W_fus which integrates different types of fly networks, listed below. The file u.sum.fly.txt is the corresponding space-separated text file. Type Source/Pubmed_ID 1. Co-expression 22378147 2. Co-expression 22296846 3. Co-expression 22556251 4. Co-expression 22434883 5. Genetic interactions BioGRID 6. Genetic interactions 18840285 7. Physical interactions 22036573 8. Physical interactions 22036573 9. Physical interactions BioGRID 10.Shared protein domains InterPro The file GO.ann.fly.15.5.13.3_300.rda contains the named 0/1 matrix GO.ann of the GO annotations release 15.5.13 for the genes in W_fus. Only GO terms with 3-300 annotated genes are considered. The file GO.ann.fly.15.5.13.3_300.txt is is the corresponding space-separated text file. The file u.sum.yeast.rda contains the squared named matrix W_fus which integrates different types of yeast networks, listed below. The file u.sum.yeast.txt is the corresponding space-separated text file. Type Source/Pubmed_ID 1. Co-expression 21964263 2. Co-expression 22289124 3. Co-expression 22621902 4. Co-expression 22306294 5. Genetic interactions 20526336 6. Genetic interactions 20691087 7. Genetic interactions 20093466 8. Genetic interactions 20139344 9. Genetic interactions BioGRID 10.Physical interactions 20489023 11.Physical interactions 20170199 12.Physical interactions 20595233 13.Physical interactions 20508643 14.Physical interactions BioGRID 15.Shared protein domains InterPro 16.Shared protein domains PFAM The file GO.ann.yeast.28.03.13.3_300.rda contains the named 0/1 matrix GO.ann of the GO annotations release 28.03.13 for the genes in W_fus. Only GO terms with 3-300 annotated genes are considered. The file GO.ann.yeast.28.03.13.3_300.txt is is the corresponding space-separated text file.